From CNN.com: Founding Fathers’ dirty campaign
Things got ugly fast. Jefferson’s camp accused President Adams of having a “hideous hermaphroditical character, which has neither the force and firmness of a man, nor the gentleness and sensibility of a woman.”
In return, Adams’ men called Vice President Jefferson “a mean-spirited, low-lived fellow, the son of a half-breed Indian squaw, sired by a Virginia mulatto father.”
Makes today’s negative campaigning seem pretty tame by comparison.